Incazelo emfushane:
Inombolo ye-CAS: 70288-86-7
Ifomula yemolekyuli:C48H74O14
isisindo se-molecule: 875.09
Isakhiwo samakhemikhali:
| Ulwazi Oluyisisekelo | |
| Igama lomkhiqizo | Ivermectin |
| Ibanga | IBanga Lezemithi |
| Ukubukeka | Impushana emhlophe |
| Isivivinyo | 99% |
| Impilo yeshelufu | iminyaka engu-2 |
| Ukupakisha | 25kg/ibhokisi |
| Isimo | Indawo eyomile epholile |
Incazelo ye-Ivermectin
Ivermectin kuyinto ejenti antiparasitic ngempumelelo ekwelapheni onchocerciasis, noma "umfula blindness". Njengoba i-ivermectin isebenza ukuvimbela isikelemu esikhulile ekukhiqizeni i-microfilariae, idinga ukulawulwa kanye kuphela noma kabili ngonyaka.I-Ivermectin ebizwa nangokuthi i-Ivomec, iwuhlobo lomuthi olunomthelela omuhle ekwelapheni izifo zezibungu.
Imiphumela ye-Ivermectin
I-Ivermectin iyi-crystalline powder emhlophe noma ephuzi ekhanyayo futhi inyibilika ku-methyl utshwala, i-ester ne-hydrocarbon enamakha kodwa amanzi. I-Ivermectin iwuhlobo lwemithi elwa namagciwane enomphumela wokushayela nokubulala kuma-nematode, izinambuzane nezibungu. Umjovo kanye ne-troche eyenziwe nge-ivermectin isetshenziswa kakhulu ekwelapheni i-nematode yamathumbu emfuyo, i-hypodermosis yezinkomo, impethu yenkonyane, impethu yempukane yezimvu, kanye notwayi lwezimvu nezingulube. Ngaphandle kwalokho, i-ivermectin ingatholakala futhi ekwelapheni i-plant-parasitic nematodes(ascarid, lungworm) ezinkukhuni. Ngaphezu kwalokho, ingenziwa futhi isibulala-zinambuzane sezolimo sokubulala izimbuzane, i-plutella xylostella, isibungu seklabishi, i-leaf miner, i-phylloxera kanye ne-nematode okuyi-parasitic ezitshalweni. Isici esivelele kakhulu salesi sibulala-zinambuzane ukuthi sinemiphumela engemihle emincane futhi singashayela futhi sibulale izinhlobo eziningi zezimuncagazi ngaphakathi nangaphandle ngesikhathi.
I-Pharmacology ye-Ivermectin
I-Ivermectin ingeyesigaba sezinto ezaziwa ngokuthi ama-avermectines. Lawa ama-macrocylic lactones akhiqizwa ukuvutshelwa kwe-actinomycete, i-Streptomyces avermitilis. I-Ivermectin iyi-ejenti ye-spectrum ebanzi esebenzayo ngokumelene nama-nematodes nama-arthropods ezilwaneni ezifuywayo futhi ngaleyo ndlela isetshenziswa kabanzi emithini yezilwane.[1]. Umuthi wethulwa okokuqala kumuntu ngo-1981. Kuye kwaboniswa ukuthi uyasebenza ngokumelene nezinhlobonhlobo eziningi ze-nematode ezifana ne-Strongyloides sp., Trichuris trichiura, Enterobius vermicularis, Ascaris lumbricoides, hook worms kanye ne-Wuchereria bancrofti. Kodwa-ke, ayinawo umphumela ngokumelene nama-flukes esibindi nama-cestodes[2].
