Incazelo emfushane:
Inombolo ye-CAS: 112811-59-3
Ifomula yemolekyuli:C19H22FN3O4
isisindo se-molecule: 375.39
Isakhiwo samakhemikhali:
| Ulwazi Oluyisisekelo | |
| Igama lomkhiqizo | 112811-59-3 |
| Ibanga | IBanga Lezemithi |
| Ukubukeka | Impushana yekristalu emhlophe ukuya kokumhlophe |
| Isivivinyo | 99% |
| Impilo yeshelufu | iminyaka engu-2 |
| Ukupakisha | 25kg/isigubhu |
| Isitoreji | Gcina endaweni epholile eyomile |
Incazelo yomkhiqizo
I-Gatifloxacin ingeyeqembu lezidakamizwa ezaziwa ngokuthi yi-quinolone antibiotics futhi isetshenziselwa ukwelapha izifo ze-acute sinus, amaphaphu, noma umgudu womchamo kanye nezifo ezithathelwana ngocansi. nge-gatifloxacin ihlanganisa isicanucanu, i-vaginitis(ukucasuka noma ukuvuvukala kwesitho sangasese sowesifazane), isifo sohudo, ikhanda elibuhlungu, isiyezi, nokushaya kwenhliziyo okungajwayelekile.Ngokuvamile, i-gatifloxacin isetshenziswa kubantu abangaphenduli kwezinye izindlela zokwelapha ze-AOM.
Ocwaningweni olulodwa, i-gatifloxacin yaqhathaniswa ne-amoxicillin/clavulanate ekwelapheni i-otitis media (OM) kanye ne-AOM ekuhlulekeni kokwelashwa ezinganeni.Izinsana ezingamakhulu amathathu namashumi amahlanu nane kanye nezingane ezinokuhluleka kwe-OM noma i-AOM okuphindaphindiwe zithole i-gatifloxacin noma i-amoxicillin/clavulanate. Imiphumela yabonisa ukuthi zombili izidakamizwa zazibekezelelwa kahle;umphumela owawuvame kakhulu wawuwuhudo.Abacwaningi baphethe ngokuthi ukwelashwa nge-gatifloxacin kanye ngosuku kwakuphumelela njenge-amoxicillin/clavulanate kabili ngosuku.Kwezinye izincwadi zezokwelapha, i-gatifloxacin iye yaqashelwa njengendlela yokwelapha yomugqa wesithathu ku-AOM.
Izicelo Zemithi
I-spectrum ihlanganisa i-Acinetobacter spp kanye ne-Aeromonas spp, kodwa ayisebenzi kakhulu ngokumelene ne-Ps.i-aeruginosa nezinye izinduku ze-Gram-negative ezingavundile.Isebenza kakhulu ezinhlotsheni ezingenwa yi-methicillin ze-staphylococci kunezinhlobo ezimelana ne-methicillin.Iphinde isebenze ngokumelene neChlamydia, Mycoplasma kanye neLegionella spp.futhi inomsebenzi othile omelene nama-anaerobes.
Icishe imunce ngokuphelele lapho inikezwa ngomlomo futhi isatshalaliswa kabanzi kuwo wonke umzimba ezicutshini eziningi zomzimba kanye noketshezi.Ukuphila kwesigamu se-plasma kungamahora angu-6-8.Ngaphezu kuka-70% womuthi ukhishwa ungashintshiwe emchamweni.Ukuvunyelwa kwezinso kuncipha ngo-57% ekungakwazini kahle kwezinso okusesilinganisweni futhi ngo-77% ekungakwazini kahle kwezinso.
Ukwelulwa kwesikhathi se-QTC kwezinye iziguli kanye nokuphazamiseka kwesifo sikashukela kuholele ekuhoxisweni komuthi emazweni amaningi ukuze usetshenziswe ngokwesistimu.I-Gatifloxacin isasetshenziswa eNyakatho Melika kuphela njengesixazululo se-ophthalmic.
Okuqhamuka uma udla imishanguzo
I-Gatifloxacin imuncwa kahle emgudwini wesisu (itholakala ngomlomo cishe i-100%), kanye nokuphathwa kanyekanye kwesidlo sasekuseni sezwekazi, i-1050 kcal, akubangakho mphumela ekutholakaleni kwayo.Umthamo ojwayelekile ngu-400 mg od futhi kokubili ukwakheka komlomo nokufakwa emthanjeni kuyatholakala.
Imiphumela emibi evamile
Ukubhebhetheka kokutheleleka ngeso
Ukucasuka kwamehlo
Ubuhlungu bamehlo
Shintsha ekunambithekeni
