Incazelo emfushane:
Inombolo ye-CAS: 137-88-2
Ifomula yemolekyuli: C14H20Cl2N4
isisindo se-molecule: 315.24
Isakhiwo samakhemikhali:
| Ulwazi Oluyisisekelo | |
| Igama lomkhiqizo | I-Oxytetracycline hydrochloride |
| Ibanga | Ibanga lokuphakelayo/ibanga le-Pharma |
| Ukubukeka | I-Crystalline powder ephuzi |
| Isivivinyo | 99% |
| Impilo yeshelufu | iminyaka engu-2 |
| Ukupakisha | 25kg/isigubhu |
| Isimo | Gcina endaweni epholile, eyomile, emnyama esitsheni esivalwe ngci noma isilinda. |
Ukwethulwa kwe-Oxytetracycline hydrochloride
I-Oxytetracycline hydrochloride iyinhlanganisela ephuzi ngokuphaphathekile, ebabayo, eyicrystalline. Isisekelo se-amphoteric sincibilika kancane kuphela emanzini futhi sincibilika kancane otshwaleni. Ayinaphunga futhi izinzile emoyeni kodwa iba mnyama lapho uchayeka elangeni elinamandla. Usawoti we-hydrochloride uyimpushana ephuzi ezinzile ebaba kakhulu kunesisekelo samahhala. Incibilika kakhulu emanzini, i-1 g incibilika ku-2 mL, futhi inyibilika kakhulu otshwaleni kunesisekelo samahhala. Zombili lezi zinhlanganisela zenziwa zingasebenzi ngokushesha ngama-alkali hydroxides kanye nezixazululo ze-asidi ezingaphansi kwe-pH 2. Zombili izinhlobo ze-oxytetracycline zimuncwa ngokushesha nangokulinganayo emgudwini wokugaya ukudla, ngakho okuwukuphela kwenzuzo yangempela isisekelo samahhala esikunikezayo ngaphezu kukasawoti we-hydrochloride ukuthi awumunyu kancane. . I-Oxytetracycline hydrochloride nayo isetshenziselwa ukulawulwa kwabazali (nge-intravenously kanye ne-intramuscularly).
Ukusetshenziswa kwe-Oxytetracycline hydrochloride
I-Oxytetracycline hydrochloride iwusawoti olungiswe ku-oxytetracycline isebenzisa iqembu eliyisisekelo le-dimethyl amino elikhiqiza kalula ukwenza usawoti kuzixazululo ze-hydrochloric acid. I-hydrochloride iwukwakhiwa okuncanyelwayo kwezicelo zemithi. Njengawo wonke ama-tetracycline, i-oxytetracycline ikhombisa umsebenzi obanzi we-antibacterial kanye ne-antiprotozoan futhi isebenza ngokubophezela kumayunithi amancane e-30S kanye ne-50S ye-ribosomal, ivimbe ukuhlanganiswa kwamaprotheni.
I-Oxytetracycline iyimithi elwa namagciwane eboniswa ekwelapheni izifo ezibangelwa amagciwane e-Gram positive kanye ne-Gram negative njenge-Mycoplasma pneumoniae, i-Pasteurella pestis, i-Escherichia coli, i-Haemophilus influenzae, ne-Diplococcus pneumoniae. Isetshenziswa ocwaningweni lwe-oxytetracycline-resistance gene (otrA). I-Oxytetracycline hydrochloride isetshenziselwa ukutadisha ukuhlanganiswa kwe-phagosome-lysosome (PL) kumaseli e-P388D1 kanye nokuthambekela kwama-antibiotic e-Mycoplasma bovis isolate.
