Incazelo emfushane:
Inombolo ye-CAS: 70458-96-7
Ifomula yemolekyuli:C16H18FN3O3
isisindo se-molecule: 319.33
Isakhiwo samakhemikhali:
| Ulwazi Oluyisisekelo | |
| Igama lomkhiqizo | I-Nofloxacin |
| Ibanga | Okuphakelayo Ibanga |
| Ukubukeka | Impushana eyikristale emhlophe ukuya kokuphuzi |
| Isivivinyo | 99% |
| Impilo yeshelufu | iminyaka engu-2 |
| Ukupakisha | 25kg/ibhokisi |
| Isici | Incibilika kancane emanzini, incibilika kancane ku-acetone naku-ethanol |
| Isitoreji | Gcina endaweni emnyama, evalwe endaweni eyomile, Emazingeni Okushisa Egumbi |
Incazelo ye-Nofloxacin
I-Norfloxacin ingeyesizukulwane sesithathu se-quinolone evimbela amagciwane eyakhiwe yi-Japan Kyorin Company ngo-1978. Inezici ze-spectrum ebanzi elwa namagciwane kanye nomsebenzi onamandla wokulwa namagciwane. Inomphumela onamandla we-antibacterial ngokumelene ne-Escherichia coli, i-pneumobacillus, i-Aerobacter aerogenes, ne-Aerobacter cloacae, i-Proteus, i-Salmonella, i-Shigella, i-Citrobacter ne-Serratia. Isetshenziswa ngokomtholampilo ekwelapheni izifo ezibangelwa ukuvela kohlobo oluthile lwe-urinary system, amathumbu, uhlelo lokuphefumula, ukuhlinzwa, i-gynecology, i-ENT kanye ne-dermatology. Ingasetshenziswa futhi ekwelapheni i-gonorrhea.
Isidakamizwa esilwa nokutheleleka
I-Norfloxacin iyisidakamizwa se-quinolone-class anti-infective enezinga eliphezulu lomsebenzi wokulwa namagciwane ngokumelene ne-Escherichia coli, i-Shigella, i-Salmonella, i-Proteus, i-Pseudomonas aeruginosa namanye amagciwane angama-gram-negative kanye nomphumela omuhle kakhulu we-antibacterial ngokumelene ne-Staphylococcus aureus, i-pneumococcus namanye amagciwane e-Gramcus. amagciwane amahle. Indawo yayo enkulu yokusebenza iku-DNA gyrase yebhaktheriya, okubangela ukuqhekeka okusheshayo kwebhaktheriya i-DNA helix futhi kuvimbe ngokushesha ukukhula nokuzala kwamagciwane, ekugcineni kubulale amagciwane. Ngaphezu kwalokho, inamandla okungena aqinile ezindongeni zeseli ukuze ibe nomphumela onamandla we-bactericidal ngokuvuselela okuncane ku-mucosa yesisu. I-Norfloxacin iyi-ejenti yokwenziwa ye-chemotherapeutic ngezikhathi ezithile esetshenziselwa ukwelapha izifo ezivamile kanye neziyinkimbinkimbi zomgudu womchamo.
Ukusetshenziswa Kwezokwelapha
Ukutheleleka komgudu womchamo oyinkimbinkimbi futhi ongaxakile (okubandakanya i-prophylaxis ezifweni eziphindaphindiwe), i-prostatitis, i-gonorrhea engavamile, i-Gastroenteritis ebangelwa i-Salmonella, i-Shigella ne-Campylobacter spp., i-Vibrio cholerae ne-Conjunctivitis (ukulungiswa kwamehlo)
