Incazelo emfushane:
Inombolo ye-CAS: 62-46-4
Ifomula yemolekyuli:C8H14O2S2
isisindo se-molecule: 206.33
Isakhiwo samakhemikhali:
| Ulwazi Oluyisisekelo | |
| Igama lomkhiqizo | I-Alpha lipoic acid |
| Ibanga | Ibanga lezemithi |
| Ukubukeka | Impushana yekristalu ephuzi ekhanyayo |
| Isivivinyo | 99% |
| Impilo yeshelufu | iminyaka engu-2 |
| Ukupakisha | 25kg/ibhokisi |
| Isici | Incibilika kancane emanzini, inyibilika kakhulu ku-dimethylformamide, inyibilika ngokukhululekile ku-methanol. |
| Isimo | agcinwe endaweni epholile neyomile |
Ukwethulwa kwe-lipoic acid
I-Lipoic acid iyisigaba sezinhlanganisela zamavithamini esigaba B futhi iyisici sokukhula imvubelo nezinye izinhlobo zezinambuzane. Ngokuvamile kubizwa ngokuthi i-Alpha-lipoic acid. Ingadlala indima ye-coenzyme ohlelweni lwama-enzyme amaningi anesibopho sokuvuselela umphumela wokudlulisa i-acyl ekuphenduleni kwe-oxidative decarboxylation ye-pyruvate ibe yi-acetate kanye nokusabela kwe-oxidative decarboxylation ye-α-ketoglutarate ibe yi-succinic acid.
Ukusetshenziswa kwe-lipoic acid
I-Alpha-lipoic acid iwuhlobo lwamavithamini B futhi ingasetshenziswa ekwelapheni isifo sokusha kwesibindi sokuqina kwesibindi esinamandla nesingapheli, isifo sokusha kwesibindi kokuqina, isibindi esinamafutha, isifo sikashukela, njll. okunye ukusetshenziswa kwe-lipoic acid kanje:
1. Hlukanisa ama-radicals mahhala.
2. Imuncwa ngokushesha futhi isetshenziswe amangqamuzana omzimba.
3. Ingaqinisa indima yamanye ama-antioxidants.
4. Ingagxiliswa ngaphakathi nangaphandle kwamaseli nolwelwesi lwamaseli.
5. Thuthukisa ukubonakaliswa kofuzo okuvamile.
6. I-Chelate metal ions, noma ikhiphe izinsimbi ezinobuthi emzimbeni.
7. I-Alpha-lipoic acid iyi-antioxidant eyenziwe ngokwemvelo emzimbeni futhi itholakala nasekudleni.
I-Alpha-lipoic acid (ALA, thioctic acid) isakhi se-organosulphur esikhiqizwa ezitshalweni, ezilwaneni nakubantu. Inezici ezihlukahlukene, phakathi kwazo amandla amakhulu okulwa ne-antioxidant futhi isetshenziswa kabanzi njengomuthi we-racemic we-diabetic polyneuropathy-associated pain kanye ne-paresthesia. Isetshenziswe kwezinye izindlela zokwelapha njengosizo olungase lube usizo ekwehliseni isisindo, ekwelapheni izinhlungu zemizwa yesifo sikashukela, amanxeba okupholisa, ukwehlisa ushukela wegazi, ukuthuthukisa ukuguquguquka kwesikhumba okubangelwa i-vitiligo, kanye nokuncipha kwezinkinga zokuhlinzwa kwe-coronary artery bypass graft (CABG).
Ngokomtholampilo, isetshenziselwa ikakhulukazi ukwelapha isifo sikashukela kanye nezinkinga zaso, i-ischemia reperfusion, i-neuropathy ewohlokayo, ukulimala kwemisebe nezinye izifo. Ngenxa yomphumela wawo oqondile wokwelapha, udingeka kakhulu ekwelashweni, ekunakekelweni kwezempilo, nasebuhleni.
