| Ulwazi Oluyisisekelo | |
| Igama lomkhiqizo | I-Lincomycin Hydrochloride |
| Ibanga | IBanga Lezemithi |
| Ukubukeka | I-crystal powder emhlophe |
| Isivivinyo | 99% |
| Impilo yeshelufu | iminyaka engu-2 |
| Ukupakisha | 25kg/isigubhu |
| Isimo | agcinwe endaweni epholile neyomile |
Incazelo ye-Lincomycin HCL
I-Lincomycin hydrochloride iyimpushana emhlophe noma emhlophe, eyicrystalline futhi ayinaphunga noma inephunga elibi. Izixazululo zayo ziyi-asidi futhi ziyi-dextrorotatory. I-Lincomycin hydrochloride incibilika ngokukhululekile emanzini; i-soluble ku-dimethylformamide futhi incibilika kancane ngethoni ye-ace.
Umsebenzi
Isetshenziselwa ikakhulukazi ukwelapha izifo ezibangelwa amagciwane e-Gram-positive ikakhulukazi amagciwane ahlukahlukene e-Gram-positive anhlobonhlobo e-penicillin, isifo sokuphefumula kwezinkukhu esibangelwa i-Mycoplasma, inyumoniya yengulube ye-enzootic, izifo ze-anaerobic ezifana ne-chicken necrotizing enterocolitis.
Ingasetshenziswa futhi ekwelapheni i-treponema dysentery, i-toxoplasmosis kanye ne-actinomycosis yezinja namakati.
Isicelo
I-Lincomycin iyi-antibiotic ye-lincosamide evela ku-actinomyces Streptomyces lincolnensis. Inhlanganisela ehlobene, i-clindamycin, itholakala ku-lincomycin ngokusetshenziswa esikhundleni seqembu le-7-hydroxy nge-athomu ene-inversion of chirality.
Nakuba kufana ngesakhiwo, i-antibacterial spectrum, kanye nendlela yokusebenza kuma-macrolides, i-lincomycin iphinde isebenze ngokumelene nezinye izinto eziphilayo ezihlanganisa i-actinomycetes, i-mycoplasma, nezinye izinhlobo ze-Plasmodium. Ukuphathwa kwe-intramuscular umthamo owodwa wama-600 mg we-Lincomycin kukhiqiza amazinga aphezulu aphezulu e-serum angu-11.6 ama-micrograms/ml ngemizuzu engama-60, futhi kugcina amazinga okwelapha amahora angu-17 kuya kwangu-20, ezintweni eziningi ezisengozini yegram-positive. Ukukhishwa komchamo ngemva kwalesi silinganiso kusuka kumaphesenti angu-1.8 kuya ku-24.8 (okusho: amaphesenti angu-17.3).
1. Ukwakhiwa ngomlomo kulungele ukwelapha izifo zokuphefumula, ukutheleleka kwesisu, izifo zemigudu yokuzala yabesifazane, izifo ze-pelvic, izifo zesikhumba nezicubu ezithambile ezibangelwa i-Staphylococcus aureus ebucayi ne-Streptococcus pneumoniae.
2. Ngaphezu kokwelashwa kwalezi zifo ezingenhla, ukwakheka komjovo kufanelekile ekwelapheni izifo ezinzima ezibangelwa i-streptococcus, pneumococcus kanye ne-staphylococcus njengokwelashwa kwe-adjuvant therapy ye-septicemia, izifo zamathambo namalunga, izifo ezingapheli zamathambo namalunga kanye ne-Staphylococcus- i-acute hematogenous osteomyelitis.
3. I-Lincomycin hydrochloride ingase futhi isetshenziselwe ukwelapha izifo ezithathelwanayo ezigulini ezingazwani ne-penicillin noma engafanele ukuphathwa kwemithi yohlobo lwe-penicillin.
