Incazelo emfushane:
Inombolo ye-CAS: 10592-13-9
Ifomula yemolekyuli: C22H25ClN2O8
Isisindo se-molecule: 480.9
Isakhiwo samakhemikhali:
| Ulwazi Oluyisisekelo | |
| Igama lomkhiqizo | I-Doxycycline Hydrochloride |
| Inombolo ye-CAS. | 10592-13-9 |
| Ukubukeka | Impushana Ephuzi |
| Ibanga | OkuphakelayoIbanga |
| Ukuncibilika kwamanzi | Incibilika emanzini |
| Isitoreji | Umkhathi ongenayo, 2-8°C |
| I-Shelf Life | iminyaka engu-2 |
| Iphakheji | 25kg/Isigubhu |
Incazelo Yomkhiqizo
I-Doxycycline hydrochloride iwuhlobo lwe-hydrochloride lwe-doxycycline, iyimithi elwa namagciwane ye-tetracycline eye yajabulela ukusetshenziswa kabanzi ekwelashweni kwezilwane nemithi yabantu ngenxa yobubanzi bayo kanye nomkhawulo obanzi wokuphepha. Amalungu okuqala ekilasi le-tetracycline ahlukaniswa nezinhlobo eziningana zamabhaktheriya ohlobo lwe-Streptomyces ngawo-1940 nawo-1950. Kusukela ngaleso sikhathi, kuye kwatholakala izinhlobonhlobo ze-tetracycline, zombili ezikhiqizwa ngokwemvelo (isb, i-chlortetracycline) kanye ne-semisynthetic (isb, i-doxycycline ne-tetracycline). I-Doxycycline yatholwa ngo-1967 futhi seyenziwe uphenyo olunzulu, kokubili ngenxa yezakhiwo zayo zokulwa namagciwane kanye nemiphumela enayo ku-physiology yezinto eziphilayo eziphakeme..
Isicelo
I-Doxycycline inesicelo esibalulekile ekwelapheni izimo ezivamile ezingapheli, njenge-acne ne-rosacea; nokho ukusetshenziswa kwayo ezinhlobonhlobo zezifo ezithathelwanayo ezingavamile, okuhlanganisa lokho uHolmes et al akuchaza ngokuthi “amabhaktheriya angavamile”, kunikeze i-doxycycline udumo oluthile “njengesidakamizwa esiyisimangaliso” noma “isikhali esiyimfihlo sikadokotela wezifo ezithathelwanayo”. Ngaphandle kokwelashwa kwayo kwezimbangela ezivamile zezifo zokuphefumula kanye ne-genitourinary tract, ezinye zezinhlelo zayo ezibanzi futhi izifo ezifana ne-rickettsial infections, i-leptospirosis, umalaleveva, i-brucellosis, kanye nenani lezifo ezithathelwana ngocansi akufanele zithathwe kancane. Ibuye ibe nezinhlobonhlobo zezicelo zamazinyo.Kuphinde kwaba nokwenyuka okungu-30% enanini lemiyalelo kulandela ukwesatshiswa kwe-anthrax bioterrorism ngo-2000–2001.10 Ngaphezu kwe-anthrax, i-doxycycline ingase isetshenziswe uma kwenzeka kusetshenziswa amanye ama-bioterrorist agents, njenge-tularaemia nesifo.1 Izicelo zesikhathi esizayo kungase futhi kuhilele ukwelashwa kwezinye izifo ezinamagciwane, njenge-lymphatic filariasis, lapho kubonakala sengathi kunesenzo ngokumelene ne-endosymbiotic bacteria ye-filariae ethile..
