Incazelo emfushane:
Inombolo ye-CAS: 24390-14-5
Ifomula yemolekyuli:C24H31ClN2O9
isisindo se-molecule: 526.97
Isakhiwo samakhemikhali:
| Ulwazi Oluyisisekelo | |
| Igama lomkhiqizo | I-Doxycycline hyclate |
| Ibanga | Ibanga lezemithi |
| Ukubukeka | ophuzi, i-hygroscopic crystalline powder |
| Isivivinyo | 99% |
| Impilo yeshelufu | iminyaka engu-2 |
| Ukupakisha | 25kg/ibhokisi |
| Isimo | agcinwe endaweni epholile neyomile |
Incazelo ye-Doxycycline Hyclate
I-Doxycycline iyilungu leqembu le-tetracycline antibiotics, futhi livame ukusetshenziselwa ukwelapha izifo ezihlukahlukene.I-Doxycycline hyclate iyimpushana ephuzi, i-hygroscopic crystalline, encibilika ngokukhululekile emanzini naku-methanol, i-soluble kancane ku-ethanol (amaphesenti angu-96), it incibilika ezixazululweni zama-alkali hydroxides nama-carbonates.
I-Doxycycline Hyclate iwuhlobo lukasawoti lwe-hyclate lwe-doxycycline, iyi-antibiotic ye-tetracycline ebanzi. Ivimbela ukwakheka kwamaprotheni ebhaktheriya ngokubopha kuma-ribosomes. I-Doxycycline iphinde ivimbele ngokukhetha i-matrix ye-metalloproteinase-8 (MMP-8) kanye ne-MMP-13 phezu kwe-MMP-1 ngokuvinjelwa okungu-50, 60, no-5%, ngokulandelana, lapho isetshenziswa ekuhlanganiseni okungu-30 μM. Ingasetshenziswa njengesilawuli sezinhlelo zenkulumo yofuzo engakholeki lapho ukusho kuncike ebukhoneni (i-Tet-On) noma ukungabikho (Tet-Off) kwe-doxycycline. Amafomula aqukethe i-doxycycline asetshenziswe ekwelapheni izifo ezibangelwa amagciwane kanye nokuvimbela umalaleveva.
Ukusetshenziswa kwe-Doxycycline hyclate
I-Doxycycline hyclate iyilungu leqembu le-tetracycline antibiotics, futhi ijwayele ukusetshenziselwa ukwelapha izifo ezihlukahlukene. Isetshenziselwa ukwelapha i-chlamydia, i-rickettsia, i-mycoplasma nezinye izifo ze-spirochete. Iphinde isetshenziselwe ukuvimbela i-matrix metalloproteinase kumithamo ye-subantimicrobial. Ivimbela i-matrix metalloproteinase kumithamo ye-subantimicrobial.
I-Doxycycline hyclate iyi-synthetic oxytetracycline derivative. Isetshenziselwe ukuqeda i-Borrelia burgdorferi kanye ne-Anaplasma phagocytophilum kuma-rodent reservoir kanye nokuqeda imikhaza ye-Ixodes scapularis. Kuyi-spectrum inhibitor ebanzi esetshenziselwa ukuvimbela i-matrix metalloproteinases(MMP), njengohlobo lwe-collagenase yohlobo loku-1 ezifundweni zokuphulukiswa kwesilonda nokulungiswa kabusha kwezicubu.
