Ulwazi Oluyisisekelo | |
Igama lomkhiqizo | I-Azithromycin |
Inombolo ye-CAS. | 83905-01-5 |
Ukubukeka | i-crystalline powder emhlophe |
Ibanga | I-Pharma Grade |
Ubumsulwa | 96.0-102.0% |
ukuminyana | 1.18±0.1 g/cm3(Kubikezelwe) |
ifomu | Kucocekile |
Ukuzinza | Izinzile. Akuhambisani nama-oxidizing agents aqinile |
Iphakheji | 25kg/isigubhu |
Incazelo Yomkhiqizo
I-Azithromycin yayingeyokuqala yama-azalides futhi yayiklanyelwe ukuthuthukisa ukuzinza kanye nengxenye yempilo ye-erythromycin A, kanye nokwenza ngcono umsebenzi wokulwa namagciwane e-Gram negative. I-Azithromycin iyimithi elwa namagciwane esebenza isikhathi eside ye-macrolide ngokwesakhiwo ehlobene ne-erythromycin A (EA), enenitrogen efakwe esikhundleni se-methyl endaweni engu-9a eringini ye-aglycone.
Isicelo somkhiqizo
I-Azithromycin ingeyama-antibiotic abanzi futhi iyi-antibiotic yesizukulwane sesibili sama-macrolides. Imiphumela eyinhloko yizifo zokuphefumula, izifo zesikhumba kanye nezicubu ezithambile ezibangelwa amagciwane azwelayo kanye nezifo ezithathelwanayo ze-chlamydia. Inomphumela omuhle wokwelapha ezifweni eziyingozi ze-bronchial ezibangelwa amagciwane omkhuhlane, i-pneumococci, ne-Moraxella catarrhalis, kanye nesifo esingamahlalakhona se-pulmonary pneumonia.Ngaphezu kwalezi zimo ezingenhla, i-azithromycin iphinde ibe umuthi osetshenziswa kakhulu ukuvimbela i-rheumatic fever. Uma isetshenziswe ngokuqinile ngaphansi kokuqondisa kukadokotela, ingabuye ihlanganiswe namalungiselelo e-dexamethasone acetate ukuvimbela ngempumelelo lesi sifo. Ingase futhi isetshenziselwe izifo ezilula zesitho sangasese ezibangelwa i-Neisseria gonorrhoeae engazweli emithini eminingi, kanye nezifo ezifana ne-chancre ebangelwa i-Haemophilus duke.Kodwa-ke, kufanele kuqashelwe ukuthi uma umuntu engezwani ne-azithromycin, erythromycin, nezinye izidakamizwa ze-macrolide, ukusetshenziswa kwazo kufanele kwenqatshelwe. Abantu abanomlando we-cholestatic jaundice kanye nokungasebenzi kahle kwesibindi akufanele basebenzise le mithi. Abesifazane abakhulelwe nabancelisayo kufanele balandele ngokuqinile iseluleko sezokwelapha futhi basebenzise imithi ngokucophelela ukuze bagweme ukuthikameza umbungu noma umntwana.