Incazelo emfushane:
Inombolo ye-CAS: 50-78-2
Ifomula yemolekyuli:C9H8O4
isisindo se-molecule: 180.16
Isakhiwo samakhemikhali:
| Ulwazi Oluyisisekelo | |
| Amanye amagama | I-acetylsalicylic acid |
| Igama lomkhiqizo | I-Aspirin |
| Ibanga | Pharma Grade/ Ibanga lokuphakelayo |
| Ukubukeka | I-crystalline powder emhlophe |
| Isivivinyo | 99% |
| Impilo yeshelufu | iminyaka engu-2 |
| Isici | Incibilika kancane emanzini, i-ethanol, i-ethyl ether, i-chloroform, isixazululo se-sodium hydroxide nesisombululo se-sodium carbonate. |
| Isitoreji | Gcina endaweni epholile eyomile |
Incazelo yomkhiqizo
I-Aspirin, eyaziwa nangokuthi i-acetylsalicylic acid (ASA), umuthi osetshenziselwa ukwehlisa ubuhlungu, imfiva, noma ukuvuvukala.Izimo ezithile zokuvuvukala i-aspirin esetshenziselwa ukwelapha zihlanganisa isifo se-Kawasaki, i-pericarditis, ne-rheumatic fever. I-Aspirin umuthi osetshenziswa kakhulu emhlabeni.
Umsebenzi
I-Acetylsalicylic acid ine-antipyretic analgesic, anti-inflammatory and anti-rheumatism effect, yingakho ivame ukusetshenziselwa imfiva, ikhanda elibuhlungu, ubuhlungu bemisipha, i-neuralgia, i-rheumatic fever, i-acute rheumatic arthritis, i-gout, njll. futhi inomphumela we-antiplatelet aggregation, futhi ingasetshenziselwa ukuvimbela i-atherosulinosis, i-atherosclerosis, i-cerebral ischemia yesikhashana kanye ne-myocardial infarction; Ngaphezu kwalokho, i-acetylsalicylic acid nayo ingasetshenziswa ekwelapheni isifo sezikelemu ze-biliary kanye nonyawo lomsubathi.
Izenzo ze-Pharmacological
I-Acetylsalicylic acid ingenye yezidakamizwa zendabuko ze-antipyretic, kanye nendima yokuhlanganiswa kweplatelet. I-Acetylsalicylic acid emzimbeni inezici ze-antithrombotic, inganciphisa ukwakheka kwamahlule egazi avimbelayo emithanjeni ezungezile, futhi ivimbele ukukhululwa kwempendulo yeplatelet kanye ne-endogenous ADP, 5-HT, njll., ngakho-ke ukuvimbela isigaba sesibili ngaphandle kwesokuqala. isigaba sokuhlanganiswa kweplatelet. Indlela yokusebenza ye-acetylsalicylic acid iwukwenza amaplatelet cyclooxygenase acetylation, ngaleyo ndlela avimbele ukwakheka kweringithoni ye-peroxide, kanye nokwakheka kwe-TXA2 nakho kuyancipha. Ngaleso sikhathi yenza i-platelet membrane protein acetylation, futhi ivimbele i-enzyme ye-membrane yeplatelet, esiza ukuvimbela ukusebenza kweplatelet. Njengoba i-cyclooxygenase ivinjiwe, iba nomthelela odongeni lomkhumbi wegazi oludidiyelwe ukuba lube yi-PGI2, i-platelet TXA2 enzymes yokwenziwa nayo okufanele ivinjwe; ngakho-ke kungaba nomthelela ekwakhekeni kwakho kokubili i-TXA2 ne-PGI2 uma kuyimithamo emikhulu. Ilungele isifo senhliziyo se-ischemic, ngemuva kwe-percutaneous transluminal coronary angioplasty noma i-coronary artery bypass grafting, ivimbela ukushaywa kwe-ischemic yesikhashana, i-myocardial infarction futhi inciphise izehlakalo ze-arrhythmia. I-Acetylsalicylic acid nayo ingasetshenziswa ekwelapheni isifo sezikelemu ze-biliary kanye nonyawo lomsubathi.
Isicelo
Yiwona owaqala ukusetshenziswa, umuthi othandwa kakhulu futhi ovame kakhulu we-antipyretic analgesics anti-rheumatism, unezici zemiphumela ye-pharmacological njenge-antipyretic-analgesic kanye ne-anti-inflammatory, anti-platelet aggregation futhi isebenza ngokushesha nangempumelelo. I-overdose ingatholwa kalula futhi ilashwe, ngokungezwani komzimba okungajwayelekile. Ngokuvamile kusetshenziselwa imfiva ebandayo, ikhanda elibuhlungu, i-neuralgia, ubuhlungu bamalunga, ubuhlungu bemisipha, i-rheumatic fever, isifo samathambo esinamandla socansi, isifo samathambo kanye nokuqaqamba kwamazinyo, njll. Kusohlwini Lukazwelonke Lwemithi Ebalulekile. I-Acetylsalicylic acid iphinde isebenze njengesimaphakathi seminye imithi.
