Incazelo emfushane:
Inombolo ye-CAS: 58-55-9
Ifomula yemolekyuli: C7H8N4O2
Isisindo se-molecule: 180.16
Isakhiwo samakhemikhali:
| Ulwazi Oluyisisekelo | |
| Igama lomkhiqizo | I-Theophylline Anhydrous |
| Inombolo ye-CAS. | 58-55-9 |
| Ukubukeka | i-crystal pow emhlophe kuya kokuphuzider |
| Ukuzinza: | Izinzile. Akuhambisani nama-oxidizing agents aqinile. |
| Ukuncibilika kwamanzi | 8.3 g/L (20 ºC) |
| Isitoreji | 2-8°C |
| I-Shelf Life | 2 Yizindlebe |
| Iphakheji | 25kg/Isigubhu |
Incazelo Yomkhiqizo
I-Theophylline iyi-methylxanthine esebenza njenge-bronchodilator ebuthakathaka. Kuwusizo ekwelapheni okungamahlalakhona futhi akusizi ekwenyukeni okukhulu.
I-Theophylline iyi-alkaloid ye-methylxanthine eyi-inhibitor yokuncintisana ye-phosphodiesterase (PDE; Ki = 100 μM). Iphinde ibe umphikisi ongakhethi we-adenosine A receptors (Ki = 14 μM ye-A1 ne-A2). I-Theophylline yenza ukuphumula kwe-feline bronchiole imisipha ebushelelezi ekhonjelwe kusengaphambili nge-acetylcholine (EC40 = 117 μM; EC80 = 208 μM). Amafomula aqukethe i-theophylline asetshenziswe ekwelapheni isifuba somoya kanye nesifo esingamahlalakhona sokuvinjwa kwamaphaphu (COPD).
Isicelo
1.Ukwelashwa kwesifuba somoya: I-Theophylline ingasiza ekudambiseni izimpawu zesifuba somoya ngokuvula amavesi e-bronchial nokwandisa ukuphumula kwemisipha.
2.Ukwelashwa kwesifo senhliziyo: I-Theophylline ingasebenza njenge-vasodilator, esiza ekuthuthukiseni izimpawu zesifo senhliziyo.
3.Ukugqugquzela isimiso sezinzwa esimaphakathi: I-Theophylline isetshenziswa kweminye imithi njengesikhuthazi sesimiso sezinzwa esimaphakathi, ikhuthaza ukuphaphama nokunaka.
4.Ukulawulwa kwe-fat metabolism: I-Theophylline ingakhuthaza ukuwohloka kwamafutha futhi kukholakala ukuthi iwusizo ekulawuleni isisindo nokulahlekelwa isisindo.
