Incazelo emfushane:
Inombolo ye-CAS: 64-75-5
Ifomula yemolekyuli:C22H25ClN2O8
isisindo se-molecule: 480.9
Isakhiwo samakhemikhali:
| Ulwazi Oluyisisekelo | |
| Igama lomkhiqizo | I-Tetracycline hydrochloride |
| Ibanga | Ibanga le-Pharma |
| Ukubukeka | I-crystalline powder ephuzi |
| Isivivinyo | 99% |
| Impilo yeshelufu | iminyaka engu-2 |
| Ukupakisha | 25kg/isigubhu |
| Isimo | Ivalwe endaweni eyomile, Gcina efrijini, ngaphansi kuka -20°C |
Incazelo
I-Tetracycline iyi-antibiotic ebanzi evimbela ukukhula kwamagciwane ngokuvimbela ukwakheka kwamaprotheni. Ibophezela kusayithi elilodwa ku-30S ribosomal subunit evimbela ukunamathiselwa kwe-aminoacyl tRNA kusayithi lokwamukela i-ribosomal. Isetshenziswa ku-cell biology njenge-ejenti ekhethiwe ezinhlelweni zesiko lamaseli. I-Tetracycline inobuthi kumaseli e-prokaryotic kanye ne-eukaryotic futhi ikhetha amaseli aphethe isakhi sofuzo sebhaktheriya se-tetR, amelana nemithi elwa namagciwane.
Isebenzisa
I-Tetracycline hydrochloride iwusawoti olungiswe nge-tetracycline usebenzisa iqembu eliyisisekelo le-dimethylamino elenza ama-protonates futhi akhe usawoti kalula ezixazululweni ze-hydrochloric acid. I-hydrochloride iwukwakhiwa okuncanyelwayo kwezicelo zemithi. I-Tetracycline hydrochloride inomsebenzi obanzi we-antibacterial kanye ne-antiprotozoan futhi isebenza ngokubophezela ku-30S kanye ne-50S sub-unit ye-ribosomal sub-unit,s blocking protein synthesis.
I-Tetracycline hydrochloride isetshenziselwa ukwenza i-apoptosis kuma-osteoclasts. Isetshenziselwa ukwelapha izinduna nezinye izifo zesikhumba, izifo zepheshana lokuphefumula njengenyumoniya, izitho zangasese, izifo zomchamo, i-leptospirosis, i-helicobacter pylori, i-taxoplasmosis, i-mycoplasma, i-psittacosis yezinja namakati. Isebenza ngokuphumelelayo nasezilwaneni ezinezifo ezithwalwa yimikhaza. Kuyasiza futhi ekusetshenzisweni kwesiko lamaseli.
Nakuba i-tetracycline isasetshenziswa njenge-antimicrobial, iningi labelaphi bezilwane ezincane bakhetha i-doxycycline kanti odokotela bezilwane ezinkulu bakhetha i-oxytetracycline lapho i-tetracycline iboniswa ukwelapha izifo ezithathelwanayo. Ukusetshenziswa okuvame kakhulu kwe-tetracycline HCl namuhla kuhlanganiswe ne-niacinamide ekwelapheni izimo ezithile zesikhumba ezivikelekile ezinjeni, njenge-pemphigus.
Izidakamizwa kanye Nokwelashwa Kwezilwane
Nakuba i-tetracycline isasetshenziswa njenge-antimicrobial, iningi labelaphi bezilwane ezincane bakhetha i-doxycycline kanti odokotela bezilwane ezinkulu bakhetha i-oxytetracycline lapho i-tetracycline iboniswa ukwelapha izifo ezithathelwanayo. Ukusetshenziswa okuvame kakhulu kwe-tetracycline HCl namuhla kuhlanganiswe ne-niacinamide ekwelapheni izimo ezithile zesikhumba ezivikelekile ezinjeni, njenge-pemphigus.
