Ulwazi Oluyisisekelo | |
Igama lomkhiqizo | I-piroxicam-beta-cyclodextrin |
Inombolo ye-CAS. | 96684-39-8 |
Ukubukeka | Ukukhanya YkahleImpushana |
Ibanga | I-Pharma Grade |
Isitoreji | Kuvalwe endaweni eyomile, Ngezinga lokushisa Legumbi |
I-Shelf Life | 3 iminyaka |
Okuqukethwe | 9.5%~11.5% |
Iphakheji | 25kg/isigubhu |
Incazelo Yomkhiqizo
I-Piroxicam beta cyclodextrin iyinqubo eyingqayizivele ehilela ukucwenga i-piroxicam yebanga lezemithi kanye ne-beta cyclodextrin yebanga lezemithi ngengxenye ethile. I-Piroxicam iwuhlobo lwesidakamizwa esingeyona i-steroidal eqeda ukuvuvukala esinemiphumela eqinile yokulwa nokuvuvukala, kodwa kunzima ukuncibilika emanzini, ukumuncwa kancane, futhi kungabangela kalula ukopha emathunjini kanye nezilonda zesisu ngemva kokuphathwa ngomlomo. Ukuphathwa kwe-intramuscular kungabangela ubuhlungu kanye ne-necrosis yezicubu ezithambile endaweni yomjovo ye-Chemicalbook. Ukulungiswa kwe-Piroxicam ku-Piroxicam- β- Cyclodextrin- β- I-complex yokufaka i-cyclodextrin ingasheshisa izinga lokuqedwa lomuthi futhi inciphise ukucasuka kwayo emgudwini wamathumbu. Isidakamizwa se-Oral analgesic Cycladol, eyaziwa nangokuthi i-Piroxicam- β- Ukusetshenziswa okuphumelelayo kwe-cyclodextrin inclusion complexes.
Isicelo somkhiqizo
I-Piroxicam beta cyclodextrin iyinqubo eyingqayizivele ehlanganisa i-piroxicam yebanga lezemithi ne-beta cyclodextrin yebanga lezemithi ngengxenye ethile ukuze kucwengwe i-Chemicalbook. Uma kuqhathaniswa ne-piroxicam monomers, le nkimbinkimbi yokuhlanganisa inephunga eliphansi, ukuzinza okuqinile, kanye nezinga lokukhululwa kwezidakamizwa ezibushelelezi, futhi isetshenziswa kakhulu emithini elwa nokuvuvukala ne-analgesic, izisetshenziswa zemithi.