Incazelo emfushane:
Inombolo ye-CAS: 1405-10-3
Ifomula yemolekyuli: C23H48N6O17S
Isisindo se-molecule: 712.72
Isakhiwo samakhemikhali:
| Ulwazi Oluyisisekelo | |
| Igama lomkhiqizo | I-Neomycin sulfate |
| Inombolo ye-CAS. | 1405-10-3 |
| Ukubukeka | Impushana Emhlophe Kuya Ephuzi Kancane |
| Ibanga | I-Pharma Grade |
| Ukuncibilika kwamanzi | Incibilika emanzini |
| Isitoreji | 2-8°C |
| I-Shelf Life | 2 Yizindlebe |
| Iphakheji | 25kg/Isigubhu |
Incazelo Yomkhiqizo
I-Neomycin sulfate iyi-aminoglycoside antibiotic kanye ne-calcium channel protein inhibitor. I-Neomycin sulfate iphinde ibophezele kuma-ribosomes e-prokaryotic avimbela ukuhumusha futhi iyasebenza ngokumelene namagciwane egram-positive kanye negram-negative. I-Neomycin sulfate inhibits PLC (Phospholipase C) ngokubopha i-inositol phospholipids. Iphinde ivimbele umsebenzi we-phosphatidylcholine-PLD futhi ibangele ukuhlanganiswa kwe-Ca2 + kanye nokusebenza kwe-PLA2 kumaplatelet womuntu. I-Neomycin sulfate ivimbela ukonakala kwe-DNA kwe-DNase I. Isetshenziselwa ukuvimbela noma ukwelapha izifo zesikhumba ezibangelwa amagciwane. Ayisebenzi ekulweni nezifo zefungal noma ezibangelwa amagciwane.
Isicelo
I-Neomycin sulfate iyimithi elwa namagciwane ye-aminoglycoside ekhiqizwa i-S. fradiae evimbela ukuhunyushwa kwamaprotheni ngokubopha ingxenye encane yama-ribosomes e-prokaryotic. Ivimba iziteshi ze-Ca2+ ezizwela imithamo futhi iyisivimbeli esinamandla sokukhululwa kwemisipha yamathambo sarcoplasmic reticulum Ca2+. I-NEOMYCIN SULFATE iboniswe ukuthi ivimbela ukushintshwa kwe-inositol phospholipid, i-phospholipase C, kanye nomsebenzi we-phosphatidylcholine-phospholipase D (IC50 = 65 μM). Isebenza kahle kakhulu ngokumelene namagciwane e-Gram-positive kanye ne-Gram-negative futhi ijwayele ukusetshenziselwa ukuvimbela ukungcoliswa kwamagciwane emiphakathini yamaseli.
