Ulwazi Oluyisisekelo | |
Igama lomkhiqizo | Ithebhulethi ye-Melatonin |
Ibanga | Ibanga lokudla |
Ukubukeka | Njengezidingo zamakhasimendeUmjikelezo, Ovali, Oblong, Unxantathu, Idayimane nezinye izimo ezikhethekile zonke ziyatholakala. |
Impilo yeshelufu | Iminyaka engu-2-3, ngaphansi kwesimo sesitolo |
Ukupakisha | Ubuningi, amabhodlela, amaphakethe amabhamuza noma izidingo zamakhasimende |
Isimo | Londoloza ezitsheni eziqinile, ezivikelwe ekukhanyeni. |
Incazelo
I-Melatonin iyi-hormone ye-amine ekhiqizwa ngokuyinhloko yi-pineal gland ezilwaneni ezincelisayo nakubantu.
Ukukhishwa kwe-melatonin kunesigqi sokujikeleza futhi ngokuvamile kufinyelela phezulu ngo-2-3 am. Izinga le-melatonin ebusuku lithinta ngokuqondile ikhwalithi yokulala. Njengoba iminyaka ikhula, ikakhulukazi ngemva kweminyaka engama-35, i-melatonin ekhiqizwa umzimba ngokwawo iyancipha kakhulu, ngokuncipha okumaphakathi kwe-10-15% njalo eminyakeni eyi-10, okuholela ekuphazamisekeni kokulala nochungechunge lwezinkinga zokusebenza, kuyilapho amazinga e-melatonin ehla futhi ubuthongo buyancipha. Ingenye yezimpawu ezibalulekile zokuguga kobuchopho bomuntu. Ngakho-ke, ukugcwalisa i-melatonin evela ngaphandle komzimba kungagcina izinga le-melatonin emzimbeni esimweni esincane, ukulungisa nokubuyisela isigqi se-circadian, hhayi nje ukujulisa ubuthongo futhi kuthuthukise izinga lokulala, kodwa okubaluleke nakakhulu, ukuthuthukisa isimo sokusebenza somzimba wonke futhi ngcono impilo. izinga futhi yehlise ijubane ukuguga.
Umsebenzi
1. Imiphumela yokuguga ye-melatonin
I-Melatonin ivikela ukwakheka kwamangqamuzana, ivimbele ukulimala kwe-DNA, futhi yehlise amazinga e-peroxide emzimbeni ngokukhipha ama-radicals mahhala, ama-antioxidants, kanye nokuvimbela i-lipid peroxidation.
2. Umphumela we-immune-modulating we-melatonin
I-Melatonin ingaphikisana nemiphumela yokuzivikela komzimba ebangelwa ukucindezeleka kumagundane abangelwa izici zengqondo (ukukhathazeka okunamandla), futhi ivimbele ukukhubazeka nokufa okubangelwa ukucindezeleka okukhulu okubangelwa izici ezithathelwanayo (umthamo ophansi wegciwane le-cerebromyocardial).
3. Imiphumela yokulwa nesimila ye-melatonin
I-Melatonin inganciphisa ukwakheka kwezithako ze-DNA ezibangelwa amakhemikhali e-carcinogens (safrole) futhi ivimbele ukulimala kwe-DNA.
Izinhlelo zokusebenza
1. Umuntu omdala.
2. Abaqwasha.
3. Labo abanekhwalithi yokulala ephansi futhi bavuswa kalula.