I-Folate Tablet (Folic Acid,Vit B9)

Incazelo emfushane:

Umjikelezo, Ovali, Oblong, Unxantathu, Idayimane nezinye izimo ezikhethekile zonke ziyatholakala.

izitifiketi

Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Ulwazi Oluyisisekelo
Igama lomkhiqizo	Amathebulethi e-Folate
Amanye amagama	Ithebhulethi Ye-Folic Acid, Ithebhulethi Ye-Folate Esebenzayo, Ithebhulethi Ye-Folic Acid Esebenzayo, njll.
Ibanga	Ibanga lokudla
Ukubukeka	Njengezidingo zamakhasimende Umjikelezo, Ovali, Oblong, Unxantathu, Idayimane nezinye izimo ezikhethekile zonke ziyatholakala.
Impilo yeshelufu	Iminyaka engu-2-3, ngaphansi kwesimo sesitolo
Ukupakisha	Ubuningi, amabhodlela, amaphakethe amabhamuza noma izidingo zamakhasimende
Isimo	Londoloza ezitsheni eziqinile, ezivikelwe ekukhanyeni.

Incazelo

Imiphumela ye-folic acid ezintweni eziphilayo ibonakala ikakhulukazi kulezi zici ezilandelayo: ukubamba iqhaza ekusetshenzisweni kwezakhi zofuzo kanye namaprotheni; okuthinta ukusebenza kokuzala kwezilwane; kuthinta ukukhiqizwa kwama-pancreas ezilwane; ukukhuthaza ukukhula kwezilwane; nokuthuthukisa amasosha omzimba.

I-Methyltetrahydrofolate imvamisa ibhekisa ku-5-methyltetrahydrofolate, enomsebenzi wokondla umzimba nokwengeza i-folic acid. I-5-Methyltetrahydrofolate iyinto enemisebenzi esebenzayo eguqulwa isuka ku-folic acid ngochungechunge lokusabela kwe-biochemical emzimbeni womuntu. Ingasetshenziswa ngokuqondile ngumzimba ezindleleni ezihlukahlukene ze-metabolic ukuze kugcinwe ukusebenza okujwayelekile komzimba, ngaleyo ndlela ibambe iqhaza ekondleni umzimba.

Umsebenzi

I-Folic acid iwuhlobo lwamavithamini B, owaziwa nangokuthi i-pteroylglutamic acid. I-5-methyltetrahydrofolate iyisinyathelo sokugcina semetabolism kanye nenqubo yokuguqulwa kwe-folic acid emzimbeni. Ngenxa yokusebenza kwayo okusebenzayo, ibizwa nangokuthi i-active. I-Folic acid iyingxenye ye-metabolic ye-folic acid emzimbeni.

Ngenxa yokuthi ukwakheka kwamangqamuzana e-5-methyltetrahydrofolate kungenziwa ngqo ngumzimba ngaphandle kokubhekana nezinqubo eziyinkimbinkimbi zokuguqulwa kwe-metabolic, kutholakala kabanzi kumaseli omzimba. Uma kuqhathaniswa ne-folic acid, kulula ukwengeza izakhi zomzimba, ikakhulukazi kwabesifazane okudingeka bazilungiselele ukukhulelwa kanye nabesifazane abakhulelwe ngesikhathi sokukhulelwa.

I-Folic acid ingenye yamavithamini abalulekile ekukhuleni nasekukhiqizeni amangqamuzana omzimba. Ukuntula kwayo kuzothinta imisebenzi evamile yomzimba womuntu. Izincwadi eziningi ziye zabika ukuthi ukuntuleka kwe-folic acid kuhlobene ngokuqondile nokukhubazeka kwe-neural tube, i-megaloblastic anemia, i-cleft lip ne-palate, ukucindezeleka, izimila nezinye izifo.

I-Neural tube malformations (NTDs)

I-Neural tube malformations (NTDs) iyiqembu lokukhubazeka okubangelwa ukuvalwa okungaphelele kwe-neural tube ngesikhathi sokuthuthukiswa kwe-embryonic, okuhlanganisa i-anencephaly, i-encephalocele, i-spina bifida, njll, futhi ingenye yezinkinga ezivame kakhulu ezisanda kuzalwa. Ngo-1991, iBritish Medical Research Council yaqinisekisa ngokokuqala ngqa ukuthi ukwengezwa kwe-folic acid ngaphambi nangemva kokukhulelwa kungavimbela ukwenzeka kwe-NTD futhi kunciphise izehlakalo ngo-50-70%. Umthelela wokuvimbela we-folic acid kuma-NTD uthathwe njengokunye kokutholwa kwezokwelapha okujabulisa kakhulu ngasekupheleni kwekhulu lama-20.

I-Megaloblastic anemia (MA)

I-Megaloblastic anemia (MA) wuhlobo lwe-anemia olubangelwa ukonakala kwe-DNA synthesis okubangelwa ukuntuleka kwe-folic acid noma i-vitamin B12. Kuvame kakhulu ezinganeni nakwabesifazane abakhulelwe. Ukukhula okujwayelekile kombungu kudinga inani elikhulu le-folic acid egciniwe emzimbeni kamama. Uma i-folic acid egciniwe iyancipha ngesikhathi sokubeletha noma ekuqaleni kokubeletha, i-megaloblastic anemia izokwenzeka ku-fetus nomama. Ngemuva kokwengeza nge-folic acid, lesi sifo singalulama ngokushesha futhi selapheke.

I-folic acid kanye nodebe oluqhekekile nolwanga

I-Cleft lip and palate (CLP) ingenye yezinkinga ezivame kakhulu zokuzalwa kokuzalwa. Imbangela yokuqhekeka komlomo nolwanga akukacaci. Ukwengezwa kwe-folic acid ngesikhathi sokukhulelwa kusencane kufakazelwe ukuthi kuvimbela ukuzalwa kwezingane ezinodebe olucake nolwanga.

Ezinye izifo

Ukuntuleka kwe-folic acid kungabangela umonakalo omkhulu komama nezingane, njengokuphuphuma kwesisu okuvamile, ukuzalwa ngaphambi kwesikhathi, ukuzalwa okunesisindo esiphansi, ukungagayeki komntwana kanye nokukhubazeka kokukhula. Izincwadi eziningi zibika ukuthi isifo se-Alzheimer's, ukucindezeleka, nokungajwayelekile kwezinzwa ezinganeni ezisanda kuzalwa nezinye izilonda zobuchopho ezihlobene nakho konke kuhlobene nokushoda kwe-folic acid. Ngaphezu kwalokho, ukuntuleka kwe-folic acid kungase kubangele nezimila (umdlavuza wesibeletho, umdlavuza we-bronchial, umdlavuza womminzo, umdlavuza we-colorectal, njll.), i-atrophic gastritis engapheli, i-colitis, isifo senhliziyo nesifo se-cerebrovascular, kanye nezinye izifo ezifana ne-glossitis kanye ukukhula okubi. Abantu abadala abangenawo i-folic acid futhi abaphuza utshwala ngokweqile bangashintsha ukwakheka kwe-mucosa yamathumbu abo.