Incazelo emfushane:
Inombolo ye-CAS: 15307-79-6
Ifomula yemolekyuli:C14H10Cl2NNaO2
isisindo se-molecule: 318.13
Isakhiwo samakhemikhali:
| Ulwazi Oluyisisekelo | |
| Igama lomkhiqizo | I-Diclofenac sodium |
| Ibanga | Ibanga lezemithi |
| Ukubukeka | I-crystalline powder emhlophe noma ephuzi kancane |
| Isivivinyo | 99% |
| Impilo yeshelufu | 4 Iminyaka |
| Ukupakisha | 25kg/ibhokisi |
| Isimo | Gcina isitsha sivaliwe endaweni eyomile, engenawo umoya. |
Incazelo ye-Diclofenac sodium
Izindinganiso zesibili zemithi zokusetshenziswa ekulawuleni ikhwalithi, zinikeza amalabhorethri ekhemisi nabakhiqizi ngenye indlela elula nengabizi ekulungiseni izindinganiso zokusebenza zasendlini.
Ihlukaniswe ngaphansi kwesigaba sezidakamizwa ezingezona ukuvuvukala (ama-NSAID). Ibonisa imisebenzi yokuvuvukala, i-analgesic kanye ne-antipyretic. I-Diclofenac Sodium iwuhlobo lukasawoti we-sodium we-diclofenac, i-benzene acetic acid ephuma kanye nomuthi oqeda ukuvuvukala (NSAID) one-analgesic, antipyretic kanye nomsebenzi wokulwa nokuvuvukala.
I-Diclofenac sodium sekuyisikhathi eside isetshenziselwa ukwelapha ubuhlungu obukhulu nokuvuvukala, futhi iyasebenza ezinhlotsheni ezihlukahlukene zobuhlungu obukhulu.
Isicelo somtholampilo mayelana ne-Diclofenac sodium
Izivivinyo zemitholampilo ziye zabonisa ukusebenza kahle kwe-analgesic ye-diclofenac sodium mayelana nokukhulula ubuhlungu obuphakathi kuya kobunzima bemva kokuhlinzwa ezigulini ezihlinzwa amazinyo noma ukuhlinzwa okuncane kwamathambo. I-subcutaneous diclofenac sodium nayo yakhulula ngempumelelo ubuhlungu obuphakathi nobukhulu be-neuropathic, obuhlobene nomdlavuza noma cha. I-Diclofenac sodium ngokuvamile yayibekezelelwa kahle ezivivinyweni zomtholampilo, ngokusabela kwesayithi lomjovo phakathi kwezenzakalo ezimbi kakhulu ezibikwayo. I-Diclofenac sodium iboniswa ekwelapheni i-arthritis ye-rheumatoid, i-osteoarthritis, ne-ankylosing spondylitis.
Izindlela zokwenza nge-Diclofenac sodium
Izindlela ezisebenzayo ze-diclofenac zingabandakanya ukuvinjelwa kwe-leukotriene synthesis, ukuvinjelwa kwe-phospholipase A2, ukuguqulwa kwamazinga amahhala e-arachidonic acid, ukukhuthazwa kweziteshi ze-potassium ze-adenosine triphosphate-sensitive potassium nge-L-arginine-nitric oxide-cyclic guanosine monophosphated pathway kanye ne-centrally mediated guanosine. izindlela ze-neuropathic. Ezinye izindlela ezivelayo zesenzo zingase zihlanganise ukuvinjelwa kwe-peroxisome proliferator activated receptor-c, ukunciphisa i-plasma kanye ne-synovial substance P namazinga e-interleukin-6, ukuvinjelwa kwe-thromboxane-prostanoid receptor kanye nokuvinjelwa kweziteshi ze-ion ezizwa i-asidi.
