Incazelo emfushane:
Inombolo ye-CAS: 23541-50-6
Ifomula yemolekyuli: C27H30ClNO10
Isisindo se-molecule: 563.98
Isakhiwo samakhemikhali:
| Ulwazi Oluyisisekelo | |
| Igama lomkhiqizo | I-Daunorubicin hydrochloride |
| Inombolo ye-CAS. | 23541-50-6 |
| Umbala | Okubomvu kuya kokubomvu okujulile |
| Ifomu | Okuqinile |
| Ukuzinza: | Ukuzinza |
| Ukuncibilika | Incibilika ngokukhululeka emanzini naku-methanol, inyibilika kancane otshwaleni, cishe ayincibiliki ku-acetone. |
| Ukuncibilika kwamanzi | Incibilika emanzini (50 mM) |
| Isitoreji | Umkhathi ongenayo, 2-8°C |
| I-Shelf Life | 2 Yizindlebe |
| Iphakheji | 25kg/Isigubhu |
Incazelo Yomkhiqizo
I-Daunorubicin hydrochloride (23541-50-6) iyi-antitumor antibiotic esetshenziswa ekwelapheni i-acute myeloid leukemias.1?Yenza ukulimala kwe-DNA ngokuhlangana.2?Yenza i-apoptosis emigqeni yamaseli ehlukahlukene.3?Ukuvimbela i-autophagy nge-chloroquine kuthuthukisa i-daunorubicin -i-apoptosis eyenziwe kumaseli e-K562.4?Iseli liyavuzwa
Isicelo
I-Daunorubicin hydrochloride imithi yokwelapha ngamakhemikhali esetshenziselwa ukwelapha izinhlobo ezithile ze-leukemia nezinye izinhlobo zomdlavuza. Ingaphansi kwesigaba semithi eyaziwa ngokuthi i-anthracyclines futhi isebenza ngokuphazamisa ukukhula nokusabalala kwamangqamuzana omdlavuza emzimbeni.
I-Daunorubicin hydrochloride ivamise ukufakwa ngomthambo uchwepheshe wezempilo endaweni yomtholampilo. Umthamo kanye nezikhathi zokwelashwa kuzoncika ohlotsheni oluthile lomdlavuza owelashwayo, kanye nempilo yonke yesiguli kanye nokusabela komuntu ngamunye emuthini.
Kubalulekile ukulandela ngokucophelela imiyalelo yomhlinzeki wezempilo yokwamukela i-daunorubicin hydrochloride kanye nokuhambela zonke izikhathi ezihleliwe zokuqapha nokuhlolwa ngesikhathi sokwelashwa. Lo muthi ungaba nemiphumela emibi kakhulu, futhi iziguli kufanele zikhulume nanoma yikuphi ukukhathazeka noma izinguquko esimweni sazo eqenjini lazo lezokunakekelwa kwempilo.
Imiphumela emibi evamile ye-daunorubicin hydrochloride ingase ihlanganise isicanucanu, ukuhlanza, ukuqothuka kwezinwele, kanye nokungenwa kalula yizifo. Imiphumela emibi kakhulu efana nezinkinga zenhliziyo nokucindezelwa komnkantsha nakho kungase kwenzeke futhi kudinga ukunakekelwa kwezokwelapha ngokushesha.
Njengayo yonke imithi yokwelapha ngamakhemikhali, i-daunorubicin hydrochloride kufanele isetshenziswe kuphela ngaphansi kokuqondisa kukachwepheshe wezempilo onolwazi ekusetshenzisweni kwemithi yokwelapha umdlavuza. Kubalulekile ukuxoxa nganoma yiziphi izimo zezokwelapha ezikhona noma imithi nomhlinzeki wezempilo ngaphambi kokuqala ukwelashwa nge-daunorubicin hydrochloride.
