Incazelo emfushane:
Inombolo ye-CAS: 74578-69-1
Ifomula yemolekyuli: C18H19N8NaO7S3
Isisindo se-molecule: 578.57
Isakhiwo samakhemikhali:
| Ulwazi Oluyisisekelo | |
| Igama lomkhiqizo | ceftriaxone sodium |
| Inombolo ye-CAS. | 74578-69-1 |
| Ukubukeka | Impushana emhlophe ukuya kokumhlophe |
| Ibanga | I-Pharma Grade |
| Isitoreji | 4°C, vikela ekukhanyeni |
| I-Shelf Life | iminyaka engu-2 |
| Iphakheji | 25kg/Isigubhu |
Incazelo Yomkhiqizo
I-Ceftriaxone iyi-cephalosporin (SEF a low spor in) isibulala-magciwane esisetshenziselwa ukwelapha izimo ezinjengokungenwa yizifo zepheshana lokuphefumula eliphansi, izifo zesikhumba nesakhiwo sesikhumba, izifo zomgudu womchamo, isifo sokuvuvukala kwezitho zangasese, i-bacterial septicemia, izifo zamathambo namalunga, kanye ne-meningitis.
Ukusetshenziswa Kwezokwelapha
I-Ceftriaxone sodium iyi-β-lactamase-resistantcephalosporin ene-serum ende ngokwedlulele uhhafu wempilo.Umthamo wemithamo kanye ngosuku kwanele izinkomba eziningi. Izici ezimbili ezinomthelela ekuqhubekeni kwesikhathi eside kwesenzo se-ceftriaxone: amaprotheni aphezulu abopha ku-plasma kanye nokuphuma kancane komchamo. I-Ceftriaxone ikhishwa kokubili ku-bile kanye nomchamo. Ukukhishwa kwayo komchamo akuthintwa yiprobenecid. Naphezu kwevolumu yayo ephansi yokusatshalaliswa, ifinyelela oketshezini lwe-cerebrospinal ekugxiliseni okusebenzayo ku-meningitis. I-pharmacokinetics engaqondile iyabonakala.
I-Ceftriaxone iqukethe i-heterocyclic system ene-acidic kakhulu eqenjini le-3-thiomethyl. Le ringsystem ye-dioxotriazine engavamile kukholakala ukuthi inikeza izici ze-pharmacokinetic eziyingqayizivele zalesi senzo. I-Ceftriaxone ihlotshaniswe “nodaka,” noma i-pseudolithiasis, etholakala kunyongo kanye nomgudu wenyongo ojwayelekile. Izimpawu ze-cholecystitis zingase zenzeke ezigulini ezithintekayo, ikakhulukazi lezo ezelashwa isikhathi eside noma esiphezulu se-ceftriaxone. I-Theculprit ikhonjwe njenge-calcium chelate.
I-Ceftriaxone ibonisa ukusebenza kahle kakhulu kwe-antibacterial-spectrum ebanzi ngokumelene ne-Gram-positive kanye ne-Gram-negativeorganisms. Imelana kakhulu nama-β-lactamase amaningi e-chromosomal andplasmid-mediated. Umsebenzi we-ceftriaxone ngokumelene ne-Enterobacter, i-Citrobacter, i-Serratia, i-indole-positiveProteus, ne-Pseudomonas spp. ihlaba umxhwele ngokukhethekile. Isebenza futhi ekwelapheni i-gonorrhea emelana ne-ampicillin kanye nezifo zomkhuhlane we-H. influenzae kodwa ngokuvamile ingasebenzi kakhulu kune-cefotaxime ngokumelene ne-Gram-positive bacteria kanye ne-B.fragilis.
