Incazelo emfushane:
Inombolo ye-CAS:62893-20-3 693878-84-7
Ifomula yemolekyuli: C25H26N9Na08S2 C8H10NNNa05S
Isakhiwo samakhemikhali:
| Ulwazi Oluyisisekelo | |
| Igama lomkhiqizo | I-Cefoperazone sodium + sulbactam sodium (1:1/2:1) |
| Umlingiswa | Impushana |
| Inombolo ye-CAS. | 62893-20-3 693878-84-7 |
| Umbala | Impushana emhlophe ukuya ensundu ngokukhanyayo |
| I-Shelf Life | iminyaka engu-2 |
| Izinga leBanga | Ibanga Lemithi |
| Ubumsulwa | 99% |
| Inombolo ye-CAS. | 62893-20-3 |
| Iphakheji | 10kg/isigubhu |
Incazelo
Incazelo:
I-Cefoperazone sodium + sulbactam sodium (1:1/2:1) iyisivimbeli esisebenzayo, i-β-lactamase esanda kwethulwa njengomkhiqizo wenhlanganisela engu-1: 1 ne-cefoperazone. Njenge-clavulanic acid, i-ejenti yokuqala yalolu hlobo ezokwethulwa, i-sulbactam ithuthukisa ukusebenza kwemithi elwa namagciwane e-β-lactam ngokumelene nezinhlobo ezingazweli.
Ukusetshenziswa:
I-semi-synthetic β-lactamase inhibitor. Isetshenziswa ngokuhlangana nama-antibiotic e-β-lactam njenge-antibacterial.
I-Cefoperazone sodium salt iyi-cephalosporin antibiotic yokuvimbela i-rMrp2-mediated [3H]E217βG ukuthatha nge-IC50 ye-199 μM. Okuhlosiwe: I-Cefoperazone ye-Antibacterial iyisibulala-magciwane, i-semisynthetic, i-spectrum ebanzi, i-parenteral cephalosporin antibiotic yokulawulwa kwe-intravenous noma intramuscular. Ngemva kokuphathwa ngomthambo i-2 g ye-Cefoperazone, amazinga ku-serum ayesuka ku-202μg/mL aye ku-375 μg/mL kuye ngesikhathi sokuphathwa kwezidakamizwa. Ngemuva komjovo we-intramuscular of 2 g we-Cefoperazone, izinga eliphakeme leserum liyi-111 μg/mL emahoreni angu-1.5. Emahoreni ayi-12 ngemuva kokuthatha umthamo, amazinga e-serum amaphakathi asengu-2 kuye ku-4 μg/mL. I-Cefoperazone iboshelwe ku-90% kumaprotheni e-serum.
