Ulwazi Oluyisisekelo | |
Igama lomkhiqizo | I-Apigenin |
Ibanga | Ibanga le-Pharma |
Ukubukeka | Impushana Ephuzi |
Isivivinyo | 99% |
Impilo yeshelufu | iminyaka engu-2 |
Ukupakisha | 25kg/isigubhu |
Isimo | Izinzile unyaka ongu-1 kusukela ngedethi yokuthenga njengoba kunikeziwe. Izixazululo ku-DMSO zingagcinwa ku -20°C isikhathi esingafika enyangeni engu-1. |
Incazelo
I-Apigenin ingenye yama-flavonoid asakazeke kakhulu ezitshalweni futhi ngokusemthethweni ingeye-flavone sub-class. Kuwo wonke ama-flavonoid, i-apigenin ingenye esatshalaliswa kakhulu embusweni wezitshalo, futhi ingelinye lama-phenolics afundwe kakhulu. I-Apigenin itholakala ngokuyinhloko njenge-glycosylated ngenani elibalulekile emifino (iparsley, isilimo esidliwayo esinamagatsha anamanzi, u-anyanisi) izithelo (amawolintshi), amakhambi (i-chamomile, i-thyme, i-oregano, i-basil), neziphuzo ezitshalweni (itiye, ubhiya, newayini). Izitshalo ze-Asteraceae, njengalezo ezingezozalo ze-Artemisia, Achillea, Matricaria, kanye ne-Tanacetum, ziyimithombo eyinhloko yalesi sithako.
I-Apigenin ingenye yama-flavonoid asakazeke kakhulu ezitshalweni futhi ngokusemthethweni ingeye-flavone sub-class. Kuwo wonke ama-flavonoid, i-apigenin ingenye esatshalaliswa kakhulu embusweni wezitshalo, futhi ingelinye lama-phenolics afundwe kakhulu. I-Apigenin ikhona ngokuyinhloko njenge-glycosylated ngenani elibalulekile emifino (iparsley, isilimo esidliwayo esinamagatsha anamanzi, u-anyanisi) izithelo (amawolintshi), amakhambi (i-chamomile, i-thyme, i-oregano, i-basil), neziphuzo ezisekelwe ezitshalweni (itiye, ubhiya, newayini)[1] . Izitshalo ze-Asteraceae, njengalezo ezingezozalo ze-Artemisia, Achillea, Matricaria, kanye ne-Tanacetum, ziyimithombo eyinhloko yalesi sithako. Kodwa-ke, izinhlobo zeminye imindeni, njenge-Lamiaceae, ngokwesibonelo, i-Sideritis ne-Teucrium, noma izinhlobo ze-Fabaceae, njenge-Genista, zibonise ukuba khona kwe-apigenin efomini le-aglycone kanye/noma i-C- kanye ne-O-glucosides yayo, Ama-glucuronides, ama-O-methyl ether, kanye nokuphuma kwe-acetylated.
Sebenzisa
I-Apigenin iyi-antioxidant esebenzayo, eqeda ukuvuvukala, i-anti-amyloidogenic, i-neuroprotective nethuthukisa ingqondo enamandla athakazelisayo ekwelapheni/ekuvinjweni kwesifo i-Alzheimer's.
I-Apigenin ikhonjiswe ukuthi ine-antibacterial, antiviral, antifungal, kanye nemisebenzi ye-antiparasite. Nakuba ingeke ikwazi ukumisa zonke izinhlobo zamagciwane iyodwa, ingahlanganiswa namanye ama-antibiotic ukuze kwandiswe imiphumela yawo.
I-Apigenin iyi-reagent ethembisayo yokwelapha umdlavuza. I-Apigenin ibonakala inamandla okuthuthukiswa njengesengezo sokudla noma njenge-adjuvant chemotherapeutic ejenti yokwelapha umdlavuza.