Incazelo emfushane:
Inombolo ye-CAS: 137-88-2
Ifomula yemolekyuli: C14H20Cl2N4
isisindo se-molecule: 315.24
Isakhiwo samakhemikhali:
| Ulwazi Oluyisisekelo | |
| Igama lomkhiqizo | I-Amprolium Hydrochloride |
| Ibanga | Ibanga lokuphakelayo |
| Ukubukeka | Impushana emhlophe yeCrystalline |
| Isivivinyo | 99% |
| Impilo yeshelufu | iminyaka engu-2 |
| Ukupakisha | 25kg/isigubhu |
| Isimo | Gcina endaweni epholile, eyomile, emnyama esitsheni esivalwe ngci noma isilinda. |
Ukwethulwa kwe-Amprolium Hydrochloride
I-Amprolium iyi-analog ye-thiamine kanye ne-antiprotozoal ephazamisa ukwakheka kwe-thiamine futhi ivimbele ukuhlanganiswa kwe-carbohydrate. Ngokuncintisana ivimbela ukumuncwa kwe-thiamine yi-E. tenella schizonts kanye namaseli amathumbu abamba amaphuphu (Kis = 7.6 kanye no-326 μM, ngokulandelana). Iphinde ivimbele ukwakheka kwe-hexose kanye nokusetshenziswa kwe-pentose ex vivo kuma-erythrocyte egundane elingalodwa kanye nasesibindi, izinso, inhliziyo, kanye nama-homogenates ezicubu zamathumbu kulandela ukuphathwa kokudla. I-Amprolium (1,000 ppm ekuphakeleni) ivimbela ukuphuma kwe-oocyst kanye ne-sporulation ye-Eimeria maxima, E. brunetti, ne-E. acervulina kumatshwele anegciwane. Iphinde yehlise isilonda kanye nezikolo ze-oocyst nokufa kwamatshwele ane-E. tenella-infected kulandela ukulawulwa kokudla komthamo we-125 ppm. I-Amprolium (100 μM) yenza i-apoptosis kumaseli e-adrenal rat we-PC12 futhi inyuse izinga le-caspase-3 eqhekekile. Amafomula aqukethe i-amprolium asetshenziswe njengama-coccidiostats ekucutshungulweni kwezinkukhu.
Ukusetshenziswa kwe-Amprolium Hydrochloride
I-Amprolium Hydrochloride inomsebenzi omuhle ngokumelene ne-Eimeria tenella kanye ne-E. acervulina enkukhu futhi ingasetshenziswa njenge-ejenti yokwelapha yalezi zinambuzane. Inomsebenzi oseceleni kuphela noma umsebenzi obuthakathaka ngokumelene no-E. maxima, E. mivati, E. necatrix, noma u-E. brunetti. Ivamise ukusetshenziswa ngokuhlangana namanye ama-ejenti (isb., i-ethopabate) ukuze kuthuthukiswe ukulawulwa kwalezo zinto eziphilayo.
Ezinkomeni, i-amprolium inemvume yokwelashwa nokuvimbela i-E. bovis ne-E. zurnii ezinkomeni nasematholeni.
I-Amprolium isetshenziswe ezinjeni, ezingulubeni, ezimvini nasezimbuzini ukulawula i-coccidiosis, nakuba ingekho imikhiqizo egunyaziwe e-USA yalezi zinhlobo.
